Are Antifungal Creams and Ointments Worth It? When and How to Use Them

Are Antifungal Creams and Ointments Worth It? When and How to Use Them

Do over-the-counter antifungal creams and ointments actually work when common infections like athlete’s foot attack? Are they a real, medically based solution? Or just a temporary fix? The truth is that these topical treatments can be highly effective for obliterating fungal infections. However, whether or not they’ll work depends on the severity of the infection, the consistency with which you use the product, and proper application.

Find out when and how to use antifungal creams and ointments to banish your infection and prevent it from coming back.

Understanding Antifungal Creams and Ointments

Antifungal creams and ointments are topical medications designed to combat fungal growth, either by stopping the fungus from multiplying (fungistatic) or by directly killing the fungal cells (fungicidal).

You’ll typically find a handful of the same key ingredients in most over-the-counter products. including:

     Clotrimazole: A broad-spectrum antifungal effective against various fungi and yeasts.

     Terbinafine: Particularly strong against dermatophytes, the type of fungi that cause athlete’s foot, jock itch, and ringworm.

     Miconazole: Another common choice for treating a range of fungal and yeast infections.

     Ketoconazole: Often used for more persistent fungal skin conditions and some types of yeast infections.

While often used interchangeably, there are subtle differences in the formulations of creams versus ointments that make them better suited for different scenarios.

Antifungal creams are lighter, water-based formulations that absorb into the skin relatively quickly. They are generally preferred for moist, weeping, or skinfold areas, i.e., between the toes or in the groin, as they allow the skin to breathe.

Antifungal ointments are thicker, oil-based preparations that create a moisture barrier on the skin. They tend to stay on the surface longer and are especially effective for dry, scaly, or cracked skin, providing an extra layer of protection.

Also read: What Are the Top Causes of Fungal Infections and the Best Anti-Fungal Treatments That Work?

When to Use Antifungal Creams and Ointments

Topical antifungal medications are most effective for localized, superficial fungal infections. Here are common conditions where they prove beneficial:

Athlete’s Foot

If you experience peeling, itching, redness, or burning sensations on your feet, especially between your toes or on the soles, an antifungal cream or ointment for tinea pedis (athlete’s foot) is a go-to treatment.

Ringworm

Characterized by a distinctive red, itchy, circular rash with raised edges, ringworm on the arms, legs, or body responds well to direct application of these topical treatments.

Jock Itch

For the itchy, red, sometimes scaly rash in the groin area, an antifungal cream can provide fast, effective relief and treatment.

Yeast Skin Infections (Candidiasis)

Folds of skin under the breasts, in the armpits, under the belly, or other areas prone to warmth and moisture can develop yeast infections. Antifungal creams formulated specifically for yeast are the go-to topical treatments.

How to Use Antifungal Creams Effectively

  1. Before each application, gently wash the affected skin with mild soap and water, then pat it completely dry. Moisture is fungus's friend, so a dry surface helps the medication absorb better and reduces the fungus's ability to thrive.
  2. Take a small amount of the cream or ointment and apply a thin, even layer. It’s important to extend the application beyond the visible edges of the rash because fungi often have microscopic tendrils that extend past the visible infection.
  3. Most over-the-counter antifungals require application one to two times daily; stick to this schedule religiously. Missing applications can prolong the infection and make it harder to eradicate. The typical treatment course ranges from one to four weeks, depending on the product and the severity of the infection.
  4. Even if your symptoms (itching, redness) improve or disappear after a few days, continue using the product for the full recommended duration. Stopping too soon is a leading cause of recurrence. The fungus might still be present, just in smaller, less active numbers.
  5. Finally, always wash your hands thoroughly with soap and water after applying antifungal cream or ointment. This helps prevent the accidental spread of the fungus to other parts of your body or to other people.

Also read: Can You Use Foot Fungus Cream on Your Hands? Here’s What to Know

When Antifungal Creams Might Not Be Enough

While highly effective for many common fungal skin infections, topical antifungal treatments have limitations, including:

Severe or Widespread Infections

If large areas of skin are affected, or if the infection is particularly deep-seated or persistent, OTC creams might not be potent enough.

Nail Fungus

Onychomycosis is notoriously difficult to treat with topical creams and ointments alone. The nail plate acts as a barrier, making it difficult for the active ingredients to reach the fungus living beneath and within the nail.

For toenail fungus on the skin of fungal nails, oral medication, laser therapy, or specialized prescription-strength lacquers are required for effective treatment.

Scalp Fungus

Like nail fungus, tinea capitis infections on the scalp are difficult for topical medications to penetrate. Oral antifungal medications are almost always necessary for effective scalp fungus treatment.

Infections That Don’t Go Away or Get Worse

If your symptoms don't show any improvement after 2-4 weeks of consistent, correct use of an antifungal cream, or if the infection worsens, it’s time to seek professional medical attention.

Tips for Supporting Treatment and Preventing Recurrence

     Keep Skin Clean, Dry, and Breathable: Shower daily, dry thoroughly, especially in skin folds. Wear breathable fabrics like cotton that wick away moisture.

     Rotate Shoes and Wear Moisture-Wicking Socks: For athlete’s foot treatment, don't wear the same shoes two days in a row. Let them air out, and wear socks made from synthetic materials that draw moisture away from the skin.

     Disinfect Surfaces: Regularly clean and disinfect shower floors, gym equipment, and shared surfaces. And don’t forget to do your footwear; doctor-formulated antifungal spray is incredibly helpful for killing fungus in shoes.

     Avoid Sharing: Towels, nail clippers, socks, and other personal items should stay personal to avoid spreading fungi.

Also read: Is It Just Dry Skin Or a Fungal Infection on Your Hands or Feet?

When to See a Doctor

     If the infection doesn't improve after 2-4 weeks of consistent, proper over-the-counter athlete’s foot treatment or other topical application.

     If you notice signs of the infection spreading rapidly, causing severe pain, developing pus, or showing other signs of a secondary bacterial infection.

     If you suspect toenail fungus or scalp fungus, as these often require stronger, prescription-strength antifungal creams or oral medication options.

     If you have underlying health conditions like diabetes, a weakened immune system, or poor circulation.

Antifungal Soaks & Sprays: The Mess-Free Alternatives to Ointments & Creams

For mild, localized issues like athlete’s foot, ringworm, and jock itch, antifungal ointments and creams can be used for effective treatment. If applied consistently and correctly, they can provide significant relief and successfully eradicate the infection.

The biggest downside? These topicals can be pretty messy and are less hygienic compared to antifungal sprays and soaks.

Dr. AntiFungus Hand + Foot Spray and Hand + Foot Soak are mess-free for fast-acting relief and eradication of fungal infections. Learn more about these doctor-formulated, doctor-recommended products today!

What's Inside: Our Ingredients
Every ingredient in Dr. AntiFungus products is carefully selected to maximize efficacy, comfort, and safety.
Here’s a closer look at how our innovative formulas work:


Tolnaftate Our hero ingredient, tolnaftate, is a powerful antifungal agent that stops fungal growth at the source. By weakening the fungal cell wall, it helps cure existing infections and prevents their spread. Commonly found in creams and sprays for athlete’s foot, jock itch, and ringworm, tolnaftate relieves itching, burning, cracking, and scaling caused by fungal infections.

Fun Fact: We’re the first to incorporate tolnaftate into a water-based soak for superior absorption and effectiveness.